European Journal of Molecular & Clinical Medicine

There are approximately 3000 species of snakes existing in Earth, of which only 600 species are poisonous. Snake population, venom composition and related human health hazards are variable in geographic areas and seasons.
Aims: To work out predictive factors of requirement of Invasive and Non-Invasive Ventilation in Neurotoxic snake envenomation.
Materials and Methods: The present study was a Prospective, observational and analytical study. This Study was conducted for one year at N.R.S. Medical College and Hospital, Kolkata
Result: In our study, Krait bite was responsible for maximum no. of envenomation in the study population (69%) followed by unknown snake bite (21.5%), whereas cobra bite was least among study population (9.5%) and Maximum no. of patients presented to Health Centre within 6 hours, where they were given initial 10 vials of ASV (69%).
Conclusion: Presence of dysphagia, pain abdomen, ophthalmoplegia, hypotension and others (neck weakness, limb weakness and unconsciousness) were found to be statistically associated with development of respiratory paralysis

Miller Fisher syndrome(MFS) is a likely variant of Guillain-Barre syndrome(GBS). Here, we present a case with peculiar demonstration of MFS as per the patient was found to have areflexia , ptosis left right distal with absent positional ,vibration sense and positive Romberg’s signs. There was history of pricking sensation in both Upper limb/Lower limb and swaying while walking, more towards the right. It was concluded as MFS from the clinical reports and the history taken. The infirm was started on methylprednisolone 1gm was given for 5 days followed by tapering dose of oral steroids along with Physiotherapy. Patient improved during the course in hospital and became stable. This event, point out the facts of a atypical disorder, which able us to limit the discrepancies to work out rapidly and properly handle such infirm. The anti GQ1b immunoglobulinG antibody is a definite marker of Miller Fisher syndrome, thus helps in the diagnosis of MFS. This moreover shows the importance of taking the history and medical assessment.