Background: Cervical cancer is the second most common cancer in India. The pathogenesis from low grade CIN to cervical cancer takes from 10 to 20 years, during which timely screening for premalignant lesions and early treatment is highly effective in preventing overt disease. Aims: To study the morphometric parameters of the LBC Pap smear and correlate with morphometric parameters, exploring it’s possible role to improve the sensitivity and specificity for detection of premalignant and malignant conditions. Design: Prospective analytical study. Methods and Material: The morphometric analysis was conducted on 200 LBC cervical samples which included normal and abnormal case findings. 20 intermediate squamous cells per slide were evaluated using Nikon instrument software. Cases screened and reported as squamous cell abnormality, cases showing reactive cellular changes and cases having normal cytology were included. The parameters evaluated were cell area, cell perimeter, nuclear area, nuclear diameter, nuclear perimeter and N:C ratio. The LBC technique used was Surepath test. Statistical analysis used: The parameters between the normal and abnormal Pap smear groups were compared using UNPAIRED t-test. Software used was SPSS Version21. Results: It was observed that there was increase in N:C ratio, nuclear area, nuclear diameter, nuclear perimeter from normal to squamous epithelial lesions. Mean cell area and mean cell perimeter was more in normal cells compared to abnormal squamous epithelial lesion. Conclusion: Morphometry can be used as a diagnostic tool in differentiating between premalignant and malignant lesions of cervix