European Journal of Molecular & Clinical Medicine

Background: Ageing is a normal process. There has been an expansion of geriatric age
group due to increased longevity. In developing countries the prevailing socio-economic
conditions of elderly, the process of ageing along with suffering from various health and
social problems definitely affect the day to day of an individual’s life during the old age.
Objectives: To evaluate health profile of geriatric population, To describe the various
types of morbidity with the advancing age.
Materials and This study is a prospective cross sectional study design conducted in
slums of Rajahmundry city for 3 months. The sampled population (484) is divided in to
three categories as per division of age i.e., 60-64 yrs, 65-74 yrs and ≥75 yrs. Medical
problems, psychological problems and other problems are being assessed through
administered study questions.
Results: In the age group of 60-64yrs Hypertension is the major health problem present
in respondents. Next to hypertension individuals have reported to be suffering from
Diabetes. Fatigue is the major psychological problem present in respondents. Next to
Fatigue Lack of Sleep is found to be second major psychological problem. Tobacco
consumption is found in all age group whereas lack of physical exercise followed next.
Conclusion: This study highlighted that majority of the elderly people are affected by
medical and social problems, thus the focus should be on strengthening of geriatric
health services along with social support so that the elderly people may be looked timely
and regularly for their morbidity care so as to deal a happy daily life.

Background:Neuropsychological assessment is the normatively informed application of
performance-based assessments of various cognitive skills. The present study was conducted
to evaluate neuropsychiatric illnesses in geriatric group.
Materials & Methods: 134 subjects age > 60 years with some neuropsychiatric illnesses of
both genders were enrolled. Parameters such as alcohol dependence with or without various
complications, mood disorder-mania, organic mental disorders, psychosis and mood disorderdepression
was recorded
Results: Out of 134 subjects, males were 84 and females were 50. Common neuropsychiatric
illnesses were schrizophrenia in 22, mood disorder in 18 and anxiety disorder in 12, organic
mental disorder in 48 and alcohol dependence in 34. The difference was significant (P< 0.05).
Conclusion: Organic mental disorder and alcohol dependence were most common
neuropsychiatric illness in geriatric population.

Introduction: Geriatric populations are vulnerable population for adverse drug reactions due to their pharmacokinetic limitations. ADR in older people are common cause of admission to hospital [1, 2] and important causes of morbidity and mortality. In more recent studies, the ADR rate in geriatric setting for the USA and Europe was greater (20%) than in studies carried out in general medicine settings [3]. In tribal distict, the availability of qualified doctors is an important issue, which may predispose to self- medication of modern medicines. There may also be use of various traditional medicines by quacks without prescription of authorized BAMS doctors). There is common concept that Traditional medicines are safer but reliable information (systematic toxicological evaluation) is not available [4]. Use of traditional medicine may associated with various adverse reaction that can affect oral health.

Introduction: The use of aspirin as a pain reliever has been in use for the past 10 years.
Its therapeutic use has also been proven to prevent heart attack and other related
ailments. Elderly individuals who are at greater risk are mostly prescribed low dose
aspirin as an anti-platelet drug to prevent thrombosis.
Materials and Methodology: Aspirin drug with a dose of 100 mg/day was administered
either through oral route or by a nasogastric tube after having breakfast for a period of
2 weeks and then the drug was stopped, and the investigations were continued for a
further 3 weeks. Blood samples and 24hour urine samples were collected every week:
before the administration of first dose of aspirin, and at the end of every treatment
week, and continued for further 3 consecutive weeks after the discontinuity of aspirin
drug. Student’s paired t-test is used to check for the weekly changes of all
measurements compared to baseline, multivariate analysis of variance with repeated
measures (MANOVA) for the overall effect of aspirin drug during the study period.
Results: A highly significant association between the variations from baseline to week 2
in both creatinine and Cu acid was recorded (r = 0.7, P < 0.0001). However, such
correlations were not found between changes in values of C-G and Cu acid. The
decrease in Ccr was also influenced by low haemoglobin levels (R2 = 0.075, P = 0.006)
and by albumin levels with borderline significance (R2 = 0.027, P = 0.08).
Conclusion: The results of the present study might directly reflect that the low dose
aspirin administration in elderly inpatients for a relatively briefer period of time has a
significant effect on their renal tubular function; hence a long-term drug intake may
have some major harmful effect on renal activity. These findings have received a major
necessity to conduct further research in younger and healthier patients and also on
long-term usage of aspirin therapy