European Journal of Molecular & Clinical Medicine

Background: Many imaging modalities, such as USG, CT, and Invasive Cholangiography, have limitations and poor visualization of intraductal stones and leads to the requirement for intrusive procedures like ERCP and PTC. MRCP is a non-invasive imaging modality, which provides good visualization of the hepatobiliary system.
Aim and Objectives: To study the role of MRCP in screening and diagnosing pancreatico -biliary diseases and to study the imaging appearance of pancreatico-biliary diseases on Magnetic Resonance Cholangio-Pancreatography.
Materials and Methods: A correctional study of 50 patients of pancreatico-Biliary diseases were evaluated with MRCP using 1.5 T MRI attending KBNTGH attached to KBNUFMS, kalaburagi, over a period of one and half year
Results: Out Of the 50 patients, 31 were male and remaining 19 were female patients. The patients of > 40 years had the highest number of instances. Out of 50 patients who underwent MRCP, 14 has cholangiocarcinoma (Males-9 & Females-5), 11 patients had Pancreatits (Males-8 & Females-3), 07 had Choledocholithiasis (Males-2 & Females-5), 06 had Periampullary carcinoma, 05 patients had Carcinoma pancreas, 03 patients had Carcinoma Gall bladder, and other had post-operative stricture, choledochal cyst. Biliary strictures were seen in 12 patients, out of which 5 had benign strictures and 7 were malignant.
Conclusion: MRI and MRCP have been proven to be sensitive, non-invasive imaging modalities that aid in the early detection and diagnosis of disease as well as in providing crucial details of therapeutic and prognostic implications.

Aim: To compare the diagnostic accuracy of Magnetic Resonance Cholangiopancreatography (MRCP) with Ultrasound and Computed Tomography (CT) in evaluation of patients with obstructive jaundice.

Aim: To compare the diagnostic accuracy of Magnetic Resonance Cholangiopancreatography
(MRCP) with Ultrasound and Computed Tomography (CT) in evaluation of patients with
obstructive jaundice.
Methodology: This study was conducted in the Department of Radio Diagnosis, Maharishi
Markandeshwar Medical College and Hospital, Kumarhatti, Solan for the period of 6 months.
60 patients clinically diagnosed as suffering from obstructive jaundice and having total
Bilirubin greater than 5mg/dl were included in this study. Patients who were pregnant and
claustrophobic were not included in this study. All the patients were instructed to fast
overnight prior to examination. Renal functional status, clinical history of all the patients was
noted before undergoing contrast CT. All the patients in the study underwent USG
examination first followed by MRCP and finally CT. Both curvilinear and linear probes were
used in the study. Images of the biliary tree were recorded for later review. Helical CT was
performed on a Philips Healthcare 128 slice CT scanner. MRCP was performed on Philips
Healthcare 1.5 Tesla MRI Scanner. All images were obtained with breath holding and
parameters were individualized.
Results: Of 60 patients, 16 (26.7%) patients were ≤45 years and 44 (73.3%) were >45 years.
32 (53.3%) cases were males and 28 (46.7%) were females. There were 37 (61.7%) patients
with ≤40 days of duration of symptoms and 23 (38.3%) patients with >40 days of duration of
symptoms. In causes of obstruction, choledocholothiasis was responsible
for19(31.7%),stricture16(26.7%),carcinoma ofheadofpancreas11(18.3%),
gallbladdercarcinoma6 (10%), periampullary carcinoma5(8.3%) and cholangiocarcinoma in 3
(5%) of the cases. Taking MRCP as gold standard, 100% (60 cases) had obstructive jaundice.
Whereas 56.7% (34 cases) were diagnosed correctly using USG and 86.7% (52 cases) were
diagnosed correctly using CT. The sensitivity of MRCP is 94% and CT is 92%, while it is
100% for USG. Inspite of the high sensitivity for USG, the specificity for the same is very
low at 70% when compared to that of CT’s 72% and MRCP’s 100%.
Conclusion: The only drawback of MRCP is the cost involved and the availability. From this
study, It is recommended that helical CT can be used as a screening imaging technique to
identify the presence or absence of intrahepatic biliary duct dilatation; thereby shortlisting the
patients for MRCP examination.

Background: Stroke specifically the type due to cerebrovascular disease is defined as a sudden, non-convulsive focal neurological deficit. The terms “apoplexy” originating from the Greek and insult from the Latin “insultus” described stroke phenomenon in ancient times. Cerebrovascular accident is a leading cause of death and disability throughout the world. It is a common cause of death after heart disease and cancer in India. Accurate and early diagnosis can improve the morbidity and mortality rates, as newer and more effective therapies are currently being instituted. Since computed tomography imaging is widely available, cost effective and less time consuming, it plays the role of first line imaging modality.
Aims and objectives: The purpose of the present study is to document the presence or absence of haemorrhage or infarcts, to determine the location and reasonably assessing the territory to blood vessels involved and to detect the incidence of negative cases of clinically suspected stroke.
Materials  and  Methods:  A prospective study of 62 cases admitted to Department of Radiodiagnosis, Government Medical College, Baramulla, Jammu and Kashmir, India with the clinical diagnosis of acute stroke were taken up for the study. Data for my study is collected by sampling referred cases with a clinical history of stroke.
Results: Out of 62 patients clinically suspected of CVA submitted for CT scan study of the brain. 40 patients i.e., 64.5% had infarcts. 15 patients i.e., 24.2% had haemorrhage, 3 patient i.e., 5% had S.D.H., 2 patients i.e., 3.33% had C.V.T. 1 patient i.e., 1.6 % had tumour and 1 patient i.e., 1.6% had normal scans. Infarcts formed the major group of the CVA cases i.e., 64.5%, involving most commonly the R.M.C.A. territory in patients i.e., 26.31%. Haemorrhage formed the second major group of the CVA cases i.e., 25%, involving most commonly the L.M.C.A. territory in patients i.e., 26.66%.