Online ISSN: 2515-8260

Keywords : Convulsions

A Clinical Study of Maternalandperinatal Outcome in Pregnancy Induced Hypertension

Himabindu Sangabathula, Neelima V, Siddareddy Yashovardhini

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 3, Pages 4767-4777

Background:Hypertension is a prevalent and serious disorder that can cause or
exacerbate many health issues. Blood pressure is directly associated to cardiovascular
disease and mortality. Stroke, MI, angina, heart failure, renal failure, and
cardiovascular mortality are all linked to BP. As a result, hypertension is often referred
to as "the silent killer." The study's aim is to assess maternal morbidity and mortality
in pregnant women with pregnancy-induced hypertension. Birth weight, Apgar score,
NICU admission, prenatal morbidity and mortality.
Materials and Methods: During two years, pregnant women aged 21 to 40 weeks were
studied at Govt Medical College &Hospital Nalgonda (July 2019-July 2021). An 80-
patient study. The institutional ethics committee review board approved. Each patient
had a comprehensive history, clinical examination, and proforma. In all instances, the
length of hospital stay, patient recovery, perinatal outcome (birth weight, Apgar score,
NICU admission), and perinatal morbidity and mortality were examined.
Results: he present investigation found that unbooked cases had more severe
preclampsia and eclampsia. Preeclampsia patients who had not had routine prenatal
care were 40 percent unbooked. Unbooked cases have increased maternal and perinatal
mortality. In this study, 40% of NICU admissions were due to LBW/asphyxia. Overall,
50% of newborns were born underweight. PIH was a prominent cause of iatrogenic
premature birth.
Conclusion: 100% registration of pregnant women and good quality antenatal
treatment including weight, blood pressure, and urine analysis with adequate referral
mechanism to tertiary care centres.All family physicians and medical officers need to be
advised to follow a standard management protocol in a case of preeclampsia and
eclampsia with an awareness for prompt referral of women who require to be managed
by specialist. Every tertiary care centre must have specialised expertise. Though PIH is
not preventable, adequate ANC care can slow its progression and timely intervention
can significantly improve perinatal outcomes.

A prospective study of factors affecting maternal and perinatal outcome in eclampsia at government medical college/hospital Nizamabad

Dr Neelima Singh, Dr.Mounika, Dr Badhe Rekha, Dr.N.Sreedevi, Nidhi Singh, Dr Tharani Badikela

European Journal of Molecular & Clinical Medicine, 2022, Volume 9, Issue 3, Pages 5124-5135

Introduction: Eclampsia is one of the commonest causes of maternal deaths. The
various factors influencing maternal and perinatal outcome were evaluated in the
present study.
Aim: To determine the factors affecting maternal and perinatal outcomein Eclampsia.
Materials and methods: Present study is a prospective observational study of factors
affecting maternal and perinatal outcome in Eclampsia for a period of 6 months.
Results: The incidence of eclampsia in 1.42%. Hypertension, oedema and proteinuria
are important signs in eclampsia. The incidence of maternal mortality in the present
study was 4% and the common causes of death were acute renal failure and pulmonary
oedema. The maternal mortality in correlation with age, parity, blood pressure,
duration of labour is not statistical significant. The perinatal mortality in the present
study was 24% and corrected perinatal mortality, excluding cases of absent FHS at
admission was 18%. Prematurity was the most important cause of neonatal deaths.
Perinatal mortality was maximum in unbooked cases (37%) and is statistically
significant. Perinatal mortality was maximum, when the number of convulsions were
maximum that is in between 6-10 (100%) and it is statistically highly significant.
Conclusions: Prompt control of convulsions and blood pressure along with steps to
initiate delivery are the cornerstone and critical in Management of eclampsia.


G. G. Joag; S. Y. Ingale; D. B. POTDAR; S.B Karanjkar; Kanvikar Reshmi

European Journal of Molecular & Clinical Medicine, 2020, Volume 7, Issue 1, Pages 4125-4129

Present study is to assess the incidence of hypomagnesemia and hypocalcemia on day one and day four in neonates who are born in a tertiary care hospital of western maharashtra. Study done at KRISHNA Hospital, Karad. Children s who were born congenitally, and who met the eligibility criteria, were studied in the obstetric department of Krishna Hospital. 2.5 ml of cord blood was collected on day 1 of life in a plain bulb. On Day 1 of life, Hypocalcemia occurred in 0.5% of the 400 neonates studied. On Day 1 of life, Hypomagnesemia occurred in 1% of the 400 neonates studied. On Day 4 of life, Hypocalcemia occurred in 10.5% of the 400 neonates studied. On Day 4 of life, Hypomagnesemia occurred in 0% of the 400 neonates studied. No cases of Hypocalcemia with Hypomagnesemia occurred together at the same time either on Day 1 of life or on Day 4 of life.