Early detection of obstructive coronary artery disease (CAD) using Peak Systolic global longitudinal strain derived by 2-D Speckle Tracking in patients with chronic stable angina. 75 patients with chronic stable angina were enrolled in this cross sectional study, (Mean age was 56.69 ± 6.96 y, 35 were males), 42.7 % were diabetic and all patients were assessed by thorough history taking, clinical examination,12 lead surface ECG, conventional, speckle Echocardiography and coronary angiography in Mansoura specialized medical hospital from march 2017 to October 2017