Background: The urinary tract infection is a significant cause for morbidity and mortality in children. The studies have shown that urinary tract infections in the early childhood are potentially dangerous, because they are the forerunners of the several renal diseases in the adulthood. Aim: The aim of this study was to evaluate the clinico-epidemiological profile of children suffering from urinary tract infection. Material and methods: This retrospective observational study was done the Department of Paediatrics, Nalanda Medical College and Hospital,Patna, Bihar, India, for 1 year, Total 100 children with culture-positive UTI were included in this study. Clinical examination was done, and the findings were recorded. Blood sampling was done for all patients and sent to a laboratory to measure total count, differential count, ESR. Results: Among 100 children’s, 64 children’s belonged to 2-5years of age constituted 64% and 36 children belonged to 5-12 years of age constituting 36%. 28 were male and 72 were female constituting 28% and 72% respectively. Most of children’s 74% came from rural area and 26% from urban areas. Most of the cases were from lower classes with 70% and 27% incidence in middle class and 3% upper class paediatric patient was admitted our hospital during the study. Among 100 children fever cases up to 61% most common symptom observed in the study. Chills and rigor were present in 39 patients with fever. Burning micturition history was present in 58 children which are around 38.7%. Increased frequency of micturition with small voids every time was present in 51 children constituting 51%. The third common symptom was abdominal pain which constituted 44%. Vomiting was present in 21 patients which are around 21% of the total. E. coli was grown in the urine culture of 59 children which was 59% of the total. Conclusion: The study group in which the risk factors were analysed had a female preponderance (may be due to the short urethra, easy ascending infection). In present study population fever and increased frequency are two important symptoms followed by abdominal pain.