Background: From the beginning of time, tuberculosis (TB) has been one of the most significant contributors to poor health, and now it is one of the most common infectious agent that results in mortality. While it most often affects the lungs, it may also manifest in other locations. Around 45 percent of the world's TB burden may be attributed to the Indian subcontinent. Around fifteen percent of all cases of tuberculosis are classified as extrapulmonary tuberculosis (EPTB). Aims and objective: To study the clinical diagnosis of abdominal tuberculosis Materials and methods: It was determined that abdominal TB affected 50 individuals. Each patient had a full battery of diagnostic procedures, including an in-depth interview and physical examination, blood work (including a complete blood count and erythrocyte sedimentation rate [ESR]), regular biochemical testing, a skin test [Mantoux], a chest X-ray, and an (USG). Results: There were 50 patients with abdominal TB (mean age 35.25±3.69 years; 20 females, 30 men). It showed that abdominal discomfort and weight loss were the most common of them. Anemia was found in 35 patients, which is 70% of the total, an increased ESR was found in 33 patients, which is 66% of the total, and hypoalbuminaemia was found in 25 patients, which is 50% of the total. Additional results included leucocytosis in three individuals (representing 6%), a positive CRP in nine patients (representing 18%), and increased transaminases in eleven patients (representing 22%). Four of these 12 patients were chronic HBV carriers, two of them had immunity to HBV, and two of them tested positive for anti-HCV antibodies. Seven individuals, or 14%, had completely normal results on all of their laboratory testing. Ten (or twenty percent) of the patients had positive results from the Mantoux skin test. Ascites was present in 21(42%) of the cases. The ascitic fluid analysis that was done on those individuals revealed that it had an exudative nature. Moreover, acid-fast bacilli were discovered in the smear of just one patient, and BacTec was only used to culture the ascitic fluid of one patient (4%). Conclusion: When it comes to the diagnosis of abdominal tuberculosis, neither the clinical symptoms, laboratory, radiographic, and endoscopic procedures, nor the bacteriological and histological results give a gold standard by themselves.