Background: Diabetes Mellitus is classified on the basis of the pathogenic process that leads to hyperglycemia, as opposed to earlier criteria such as age of onset or type of therapy. Type 2 DM is preceded by a period of abnormal glucose homeostasis classified as impaired fasting glucose (IFG) or impaired glucose tolerance (IGT). Gamma Glutamyl Transferase is involved in the transfer of amino acids across the cellular membrane and leukotriene metabolism. Given the clinical importance of an interaction between obesity and serum GGT concentrations in predicting type 2 diabetes, we evaluated possible interactions between BMI and serum GGT activity in predicting poor glycemic control and other common comorbidities of type 2 diabetes. Methods and Materials: This Study was conducted in Medicine ward of NIMS Hospital, Jaipur was considered. Approval to conduct the study was obtained from Institutional Ethics Committee before starting the study. Total number of 76 patients were considered which includes 54 males and 22 females. Only those who agreed to participate were taken. Conclusion: This Study shows the Significant Correlation between GGT with Lipid profile and HbA1c in Type 2 Diabetes Mellitus patients. These results are imperative as they back up that there is modest impact of GGT on lipid profile. Further studies with large sample size are needed to