Aim: The aim of the present study was to identify the lipid pattern in chronic kidney disease patients. Methods: The study was conducted in the Department of Medicine, Government Medical College and Rajindra Hospital Patiala, India, multi-specialty, tertiary care teaching hospital. This study was done for duration of 1 year from the date of approval of plan. 100 patients of chronic kidney disease coming to the Department of Medicine, Government Medical College and Rajindra hospital was included in the study. Results: In the present study, majority of patients, i.e. 38 (38%) belonged to the age group 45-54 years, followed by 25 patients (25%) in age group 55-64 years, 23 patients (23%) in age group 65-74 years and 14 patients (14%) in age group 35-44 years.51 patients (51%) were male and 49 patients (49%) were females. Mean value of serum Triglycerides was 161 mg/dl, serum total cholesterol was 201.5 mg/dl, serum HDL was 34.6 mg/dl, serum VLDL was 31.8 mg/dl and serum LDL was 134.7 mg/dl. The mean values of the different fractions were obtained with respect to the co-morbid conditions present in the study sample were not significant. The mean values of the different fractions were obtained in both diabetic and non-diabetic CKD patients were not significant. A similar comparison in the mean values of the lipid profile was done in patients who were on dialysis and those who were being treated conservatively and it was found non-significant. Conclusion: This study concluded that the mean values of the lipid profile in hundred CKD patients showed a borderline high range of serum triglycerides, serum total cholesterol and LDL, and decreased HDL. There was no statistically significant difference in lipid profile of male and female CKD patients.