Background: Heart failure is one of the major cause of morbidity and mortality in India and worldwide other countries. Its prevalence in the population has increased dramaticallyover time. Heart failure is a growing health problem . It is been found that the prevalence and incidence of HF are increasing, particularly in individuals aged more than 60 years. Objective: To determine gender difference in heart failure with respect to symptoms atpresentation (NYHA), clinical findings, underlying heart disease, risk factors, precipitating factors and prolonged hospital stay. Material methods: This was a cross-sectional study done in In-patients in the department of Cardiology Patna medical college and Hospital Patna Bihar. Patients who presented with symptoms and signs of heart failure secondary to cardiaccause where included in the study who fulfilled the modified Framingham’s criteria for diagnosis of HF. Study duration One and half year. Conclusion: In this study we proved that gender difference was found with regard to More of presentation of symptoms, even though males and females presented with same set of symptoms and signs, females were found to have worse symptoms at the time of admission. Females were more prone to hae Heart Failure with preserved ejection fraction, mainly at elderly age with LV diastolic dysfunction.