INTRODUCTION: Infertility has often been defined as failure to achieve pregnancy within one year of unprotected intercourse. Seminal plasma is very important for sperm metabolism, function, survival, and transport in the female genital tract. Zinc deficiency may lead to gonadal dysfunction, decrease in testicular weight and shrinkage of seminiferous tubules. Zinc may have a role in sperm production, viability and in the prevention of spermatozoa degradation. Fructose concentration is considered a good measure to evaluate seminal vesicular function and has been studied in great detail, and its concentration can depend on number of factors such as time since collection and the age of the donor.