Background: Klebsiella species has been considered as a major pathogen responsible for hospital acquired infections. Out of the six ESKAPE pathogens (Enterococcus faecium, Staphylococcus aureus, Klebsiella Pneumoniae, Acinetobacter Baumanii, Pseudomonas Aeroginosa and Enterobacter species), Klebsiella is the most encountered organism. Resistance in Klebsiella species due to production of extended spectrum beta lactamases and carbapenemases is growing, resulting in higher mortality,increased hospital stay and higher therapeutic cost .The present study highlights the need for continued monitoring of AST patterns and also emphasizes on formulation of sound antibiotic policy in the hospital.