Background&Method: This is a prospective study conducted in the Department of Radio Diagnosis, Index medical college hospital and research centre. 50 patients suspicion of prostatic pathologies were included in the study. A sample size of 50 was selected using purposive sampling technique.All the 50 patients were subjected for the multi-parametric MRI sequences including T1 and T2 weighted anatomical imaging, functional imaging using diffusion weighted MRI with ADC value calculation.The machine used in this study is GE SIGNA EXPLORER 1.5 Tesla MRI with phased array body coil. Result:Majority of lesions 37 (74%) on diffusion weighted imaging were hyperintense while 13 (26%) were hypointense. Out of 37 hyperintense lesions 24 (92.31%) were malignant on histopathology and 13 (54.16%) were benign on histopathology. 13 (26%) lesions appeared hypointense on diffusion weighted imaging 2 (7.69%) were malignant on histopathology while 11 (45.83%) lesions were benign on histopathology. This indicated benign lesions tends to both hyperintense and hypointense on diffusion weighted imaging, benign lesions those appeared hyperintense on diffusion weighted imaging had inflammatory properties ,that was confirmed on histopathology. Malignant lesions tends to be hyperintense on diffusion weighted imaging. Conclusion:Based on the findings of this study it can be concluded that DWI with ADC calculation in patients with raised PSA levels is a valuable , feasible and non-invasive method for detection and characterization of benign and malignant prostatic lesions with high sensitivity and specificity besides high predictive values and diagnostic accuracy. Multi-parametric MRI with included Diffusion Weighted Imaging along with calculation of ADC values results in best characterization of prostatic lesions and calculation of PIRADS score.