Osteoporosis, defined by the World Health Organization as a disorder of bone resulting in decreased bone strength, is an extremely common disorder of aging that currently affects 10–12 million people in the United States alone[1]. Fractures represent the main clinical manifestation of osteoporosis. Half of all women over the age of 50 years will suffer an osteoporotic fracture during their lifetime. Moreover, the increased prevalence of osteoporosis at the hip is expected to lead to a tripling of the number of hip fractures worldwide by 2050[3].The medical and economic burden of fragility fracture is substantial. When the impact of hip fracture on the quality of life is considered in disability-adjusted life years, the global burden of disease has been estimated at 1.75 million years, with approximately one-quarter occurring in China and India, and 50% occurring in Western countries alone[5]