Background: Thrombocytopenia in covid 19 patients were important for treatment and management of the disease. Main objective of the study was to assess thrombocytopenia and its association with disease severity among covid 19 patients. Methods: A cross-sectional study was conducted among 160 patients from April 2020 to December 2020.Sociodemographic and clinical data were collected. Thrombocytopenia has been implicated in patients infected with SARS Cov 2. Results: Among 160 patients, majority were males with mild severity. Platelet count were decreased in severe cases when compared to mild and moderate severity cases and found to be statistically significant(p<0.05). Conclusion: platelet count was an independent risk factor for COVID 19 patients.