Background: Patients having breast cancer, with increasing tumour size is associated with an increased of axillary lymph node involvement. Moreover, all this association to place altogether of all tumors smaller than 1.0 cm in a single category and all tumors larger than 5.0 cm in another category. This coarse classification may obscure a nuanced description of the effects of tumour size across the full range of possible sizes. Methods: Here we have studied association between primary tumour size, lymph node status cohort study of 88patients whom have been diagnosed with first primary invasive breast cancer from 2014 - 2022 in SPSS method. All patients in the cohort had a known primary tumour size between 1 and 150 mm in greatest dimension. Primary tumour size was examined as continuous (1–150 mm) and categorical variable(10-mm intervals). For each 1 or 10-mm size group, we set on the corresponding of patients with positive lymph nodes at diagnosis. Results: Amid 88 patients who is having invasive breast tumorsof size 1 and 150 mm in size, not any association of increasing tumour size and prevalence of lymph node metastases (% node-positive). For very small size of tumors (under 10 mm) and for very large size of tumors (larger than 60–90 mm) there was little correlation between European Journal of Molecular & Clinical M