Background :This research study investigates the impact of ageing on the shape and size of Meissner’s corpuscles in the great toe of the human foot. By using histological sections of thick skin were taken from 53 samples of different age groups and five samples from the foetus. we have measured H&E-stained alternate sections of thick skin of different age groups. the Meissner’s corpuscles were measured by using ImageJ software. Results: The morphometric parameters, including ranges of horizontal length (48.07m to 46.63m), vertical length (102.42m to 137.41m), perimeter (267.02m to 354.42m), area (4131.24m 2 to 5598.56m 2 ), capsule thickness (5.29m to 10.79m) and depth (9.2m to 10.79m). We did not find MC in foetal samples of a particular age group. We have also observed that the shape of the MC varies from oval, ellipsoid in shape, discoid, dumbbell shape, cylindrical, large oval shape, bean shape, inverted cone shape, triangular in shape, coiled spring shape, cone shape, and spindle in shape