ABSTRACT The study explores theory of relativity of acid levels with nephritic function, moreover as its role as a prognostic marker of cardio tube risk in chronic excretory organ diseases within the course of variable regression analysis, taking into consideration the adjustment of potential risk issues, the amount of uric acid was found to be a major factor influencing calculable capillary vessel filtration rate. The results of this study showed that elevated humor uric acid levels are related to the next risk of kidney malfunction.