Paranasal sinuses are the group of air-filled spaces developed as an expansion of the nasal cavities. These air filled cavities mostly shows the complex design and also shares relations with the adjacentstructures.Ventilation and drainage are the two most important factors in the maintenance of normal physiology of paranasal sinuses and their mucous membranes. During the study period, a total of 100 cases were evaluated who were referred from Department of ENT to the Department of radio diagnosis to evaluate the paranasal sinuses by computed tomography. The cases in acute phase of the disease were treated conservatively with a course of antibiotics, topical and oral decongestants and the cases referred after persistent symptoms and signs were counselled regarding imaging of nose and PNS by CT scan, Written informed consent was taken and data regarding the patient was collected in a case proforma. The intersphenoid septum was left sided in majority of cases i.e. 43 (43%). It was right sided in 38(38%) and in 43(%) of cases it was in central.