Abstract: This study aims to determine the effect of supplementing Moringa leaf extract plus royal jelly on levels of MDA (Malondialdehyde) in anemic pregnant women. This research is a type of Experiment research and the design used is a randomized controlled. The subject in this study were pregnant women with anemia at 20-32 weeks of gestation which consisted of 3 groups, namely the Moringa leaf extract capsule group plus royal jelly (MLERJ), the Moringa leaf extract capsule group (MLE) and the placebo group. Total of 45 subject there are (MLERJ) n=15, (MLE) n=15 and placebo n=15. The treatment is given at a dose of 1x1 in the morning for 60 days and the urine sample taken will be tested in the laboratory using the ELISA Kit and data analysis using the paired sample T test and one way ANOVA test. Characteristics based on Age, Education, Occupation, Income and Parity of the subject.The results of the one way ANOVA test were not significant, but the difference in MDA levels in the MLERJ group was higher, namely -3.64 ± (6.21) than the - 2.49 ± (4.06) MLE group and -0.37 ± (3.84) Placebo.