This laboratory study was conducted to demonstrate the effect of the biocide effect of Trichoderma harzianum, silver nanoparticles in the third larval age and the Oryzaephilus full-size beetle, and five concentrations of the biocide T. harzianum (250, 500, 1000, 2000, 4000) ppm and five Concentrations of silver nanoparticles are (1000, 2000, 3000, 5000, 10000, and 20000) ppm. The results showed that the fungicide T. harzianum had the most recent killing rates for all concentrations, as the highest killing rate for the third larval age was 96.7% at 4000 ppm during 72 hours of treatment, while the lowest killing rate for the third larval age was 16.7% at the concentration 250 ppm during 24 hours of treatment. As for the camels, the highest killing rate with the fungicide was 86.7% at the concentration of 4000 ppm during 168 hours of treatment, while the lowest killing percentage for the adult beetle was 0% at the concentration of 250 ppm within 24 hours of the treatment, as for the effect of particles Silver nanoparticles were the highest killing percentage for the third larval age 100.0% at the concentration of 5000 ppm within 72 hours of the treatment, while the lowest killing percentage for the third larval age was 13.3% at the concentration of 1000 ppm within 24 hours of the treatment. As for the adult beetle have reached the highest rate of killing 88.7% when concentrating 20000 ppm within 72 hours of treatment and concentrating 500 and 1000 ppm during 144 hours of treatment. The lowest killing rate of the adult beetle was 16.7% when concentrating 5000 ppm during 24 hours of treatment.