Volume 11 (2024) | Issue 5
Volume 11 (2024) | Issue 5
Volume 11 (2024) | Issue 5
Volume 11 (2024) | Issue 5
Volume 11 (2024) | Issue 4
Complexes of substituted isatin-3-thiosemicarbazones (H2itsc-N1 -Me, H1L; H2itsc-N1 -Ph, H2L) and substituted indole-3-thiosemicarbazone (HIntsc-N1 -Ph, H3L) with Ni (II) and triphenylphoshine of formula, [NiCl(L)(Ph3P)] (anionic form of L = 1L, 1; 2L, 2, 3L, 3) have been synthesized. The ligands and complexes have been characterized using spectroscopic techniques (IR, 1H NMR). 1HNMR of complexes supports binding of thio- ligands in anionic form. All the ligands (H1L – H3L) and their complexes were evaluated for their antitubercular activities. The enhancement in anti-TB activity of ligands on complexation with Ni(II) has been observed.