Background: Gallstone disease (GSD or Cholelithiasis) is a significant health problem both worlds over (in both developing and developed nations). The main objective is Laparoscopic cholecystectomy has rapidly become established as the popular alternative to open cholecystectomy, but it should have a safety profile better than of open procedure. Aims and objectives: The aim of this study was to compare conventional cholecystectomy and laparoscopic cholecystectomy with respect to duration of procedure, complications, postoperative pain, analgesic requirement and period of hospital stay. Materials and Methods: This study consists of 52 patients who have undergone gallbladder removal in GMC Budaun. 26 patients who have undergone laparoscopic cholecystectomy and 26 patients who have undergone open cholecystectomy for a study period of one year have been taken into the study In method 52 consecutive patients below 70 years presenting with calculous cholecystitis with no evidence of CBD stones were randomized to undergo open and laparoscopic cholecystectomy. Results: 9 patients of LC and 10 patients of OC were males. Among LC 16 patients were females and among OC group 15 were females, 28% of patients who underwent open surgery had complications and 16% of patients who underwent laparoscopic surgery had complications. The overall percentage of complications is lesser in laparoscopic surgery than open surgery, The VAS was median grade 2 in LC group as compared to median grade 4 in LC group. The NSAID’S were used for more days in OC group compared to LC group, 23 patients who underwent laparoscopic cholecystectomy were discharged before 5 days. All patients who underwent OC stayed >5 days in hospital. Conclusion: Herewe conclude in results, the duration of pain, rate of complications and hospital stay were significantly lower in laparoscopic group. However the main advantages of LC were reduced postoperative pain with less duration of analgesic intake, more rapid recovery, reduced hospital stay and early return to normal work.