Background: Craniofacial anthropometry is a method that is used to identify the morphological aspects of the head and face. Aim: The aim of the present study was to identify effect of height and weight in the prosopic (Facial) Index between male and female of Central India with Its clinical Importance. Materials & methods: A random sample of 400 students (200 males and 200 females) between the ages of 18 and 25 was taken after first obtaining approval from the ethical committee of the institution and then obtaining the participants' informed consent to take part in the study. The participants were given full disclosure regarding the nature of the study. The examination of these students did not take place until after they had provided their informed agreement to take part in the research. Everyone who agreed to take part in the study was in generally good health, and not a single one of them had ever previously undergone plastic or reconstructive surgery to treat facial deformities or injuries in the past. Results: Male have shown Hypereuriprosopic for 10 %, Euriprosopic for 26 %, Mesoprosopic for 49 %, Leptoprosopic for 10 %, and Hyperleprosopic for 5 % but none have shown significant differences when compared between the two groups of any two facial indices. The present study did not observe any significant difference when compared between the height and weight with the prosopic facial indexes of the both the genders respectively. Conclusion: A large number of people, ideally from all around the country, would need to participate in similar research in order to improve the precision of projections. As a result, the above problems will feel less weighty.