Relevance. Anesthetic manual in ophthalmology is an urgent problem of modern medicine, which is due to the specifics of intraocular operations. The relevance of anesthetic aid in ophthalmology is also increasing due to the fact that more than half of patients undergoing surgical interventions are elderly and senile patients [2,5,8,] with one or more somatic concomitant diseases [4,7,12,17,], which requires a special approach to these patients in terms of preparation for surgery, the choice of anesthesia and postoperative management. Hemodynamic disorders are one of the important links in the pathogenesis of eye diseases [10, 18]. When providing anesthesia in surgical ophthalmology, it is of great importance to take into account the state of ophthalmotonus, which is directly dependent on the hemodynamics of the eye. The works of many authors [1,7,9,11,10,] indicate that the vascular factor is one of the most important links in the mechanism of changes in intraocular pressure (IOP). Purpose of the study: To study the effect of the most frequently used anesthetics in retrobulbar blockade on the state of microcirculation of the eyes during ophthalmic operations. Material and methods. The studies were carried out in 115 operated patients with a diagnosis of acquired cataract. Patients underwent cataract extraction, extracapsular cataract extraction with intraocular lens implantation (EEC with IOL) and tunnel cataract extraction with intraocular lens implantation (EEC with IOL). The age of patients in the studied groups ranged from 50 to 86 years. More than half (84 patients - 79.2%) of them were aged 60 to 80 years. The average age was 69.6 + 5.3 years. In the allocation of the patients on the floor of the 115 female patients was 70 (62.3%) and male patients - 45 (37.7%). To study intraocular hemodynamics, Doppler ultrasound was used, which were performed them. Ultrasonic scanning was carried out on an ultrasonic Doppler by the company "Kransbuhler" at a radiation frequency of 4 and 8 MHz in a continuous mode. Many authors [13,14,15,17,19] note the relationship of hemodynamics in the orbital artery with IOP and hydrodynamics. In this regard, we present in this chapter an analysis of the results of regional hemodynamics in the studied groups of patients, since a detailed study of the hemodynamics of the eye is one of the objective parameters of the microvasculature. All patients underwent a Doppler study before and after anesthesia