Noise and vibration during the work process in the workshops of the plastic production company caused an increase in the heart rate, an increase in the pulse and minute volume of the heart, a decrease in the pulse pressure, an increase in the maximum arterial pressure and a decrease in the minimum arterial pressure. Unfavorable microclimatic conditions affecting the body of workers, increase in noise level above the norm, cause neuro-emotional stress and mobilize functional reserves in the cardiovascular system of workers. Thus, constant noise in the enterprise also affects the auditory motor response. In the first half of the working day under the influence of constant noise, adaptation in auditory analyzers and shortening of the latent time of the auditory motor reaction in workers, and at the end of the working day, fatigue occurs in the body, which indicates that the latent time of the auditory motor reaction is prolonged. When we checked the performance of the vision analyzer in the workers at the enterprise, it was observed that fatigue occurs during the work process, and the functional state of the vision analyzer decreases. It should be noted that allergic inflammatory processes are observed in workers at plastic production enterprises as a result of contact with plastic products during the working day. In order to prevent and reduce this inflammatory process, the tool "Netinfla" was studied in experimental studies. This tool caused a 67.5% reduction in inflammation compared to the control group.