Background: Median Nerve is called labourer’s nerve as it supplies large flexor muscles of forearm and five intrinsic muscles of hand which help in movement of the thumb. Comprehensive knowledge pertaining to its variations is extremely important in clinical and surgical procedures so as to avoid injury to it. The precise knowledge oflevel of origin of muscular branches of median nerve is essential in free muscular transfers to restore the mobility of fingers after trauma and to understand the variouspresentations of distribution of median nerve. Material and Methods: The study was done on 51 upper limb human cadaver specimens which were collected from dissection room from Department of Anatomy, at, Patna medical college and Hospital, Patna , Bihar. and these specimens include both adult and viable foetal cadavers, over a period of two years. The specimens obtained were fixed in 10% formalin and were finely dissected. Conclusion: In the present study an attempt is made to know the possible variations of median nerve branching pattern and termination in carpal tunnel so as to provide additional information which may help to decrease the risk of diagnostic and operative complications.