Background: To study the risk factors for recurrence of peptic ulcer disease. Materials & methods: A total of 100 subjects were enrolled. The age group included was 15 to 80 years. Possible risk factors including nonsteroidal anti-inflammatory drugs (NSAIDs), aspirin and alcohol were analysed. Recurrence rate were assessed. Student's t-test was used to compare means, chi-square test was performed. A P-value of <0.05 was considered statistically significant. Results: PUD was diagnosed using endoscopy and histology in 80 (80%) and by clinical diagnosis in 20 (20%) patients. The recurrence rate of PUD was 28% which was seen in 28 patients. Conclusion: The recurrence rate of PUD was 28%. The use of NSAID and H. pylori infection were risk factors for recurrence of PUD.