Background: Abnormal uterine bleeding (AUB) is a major clinical problem in women of peri and post-menopausal age group. It accounts for 30%of outpatient population coming to a gynaecologist. Evaluation of AUB is important for ruling out endometrial carcinoma and its precursors. Endomed biopsy is an ideal method for obtaining endometrial sample with ease, low cost and without anaesthesia. To determine sensitivity, specificity, positive predictive value and negative predictive value of Endomed sampler, by comparing the histopathology reports of endometrial samplings with that of hysterectomy specimen, taken as gold standard. Methods: This study is carried out in 76 patients with abnormal uterine bleeding posted for hysterectomy.