ABSTRACT Hemoglobin and myoglobin are heme proteins that can bind oxygen reversibly and were first reported in vertebrates. Later on, occurrence of hemoglobin was found in all forms of life ranging from prokaryotes to eukaryotes. Myxobacteria are Gram-negative, rod-shaped eubacteria and that belong to delta proteobacteria. They predominantly thrive in soil and have very large genome size with high G+C content in comparison to other eubacteria. It is evident that the globins have been characterized predominantly from bacteria involved in photosynthesis, nitrogen fixation andpathogenicity, where these are implicated in and the protection of photosynthetic machinery from the oxidative damage,protection of nitrogen fixing enzyme from nitrosative and oxidative stress and the virulence of the host, respectively.