Background: In India, cardiovascular disease (CVD) is the main cause of morbidity and mortality. According to recent trends, this group of disorders has expanded to younger age groups as well. Cardiovascular illnesses are on the rise in India, affecting both men and women in both urban and rural areas. The objective of this study was to analyse serum uric acid levels correlate these values with Killip class in patients of acute MI. Materials and Methods: Study was prospective type conducted at Dr. Baba SahebAmbedkar Medical College and Hospital, Rohini, New Delhi from September 2016 to August 2017. A total of 100 patients of acute MI admitted to the ICCU, falling into inclusion criteria were enrolled. Information was collected through a pre tested and structured proforma for each patient. Also, physical examination and laboratory investigation with special reference to Killip classification of heart failure was carried out. During data analysis, a p value of <0.05 was considered statistically significant. Results: Mean age of population 54.77 years. This study population had male predominance (69.0%). In our study out of 100 patients 85 (85%) patients were STEMI and 15 (15%) patients were NSTEMI. Mean uric acid on day 7 in patients with Killip class I was 4.72 mg/dl and subjects with Killip class II was 6.62 mg/dl. In multivariate logistics regression no factors were significantly affecting mortality after adjusting for confounding factors. Conclusion: From our study, we conclude that serum uric acid levels are correlated with Killip class and patients with higher Killip class have higher serum uric acid levels in acute myocardial infraction.