Background: According to the pressure natriuresis theory, monogenic hypertension, and dietary salt reduction studies, Na+ is a primary predictor of blood pressure and mortality. The evolved response to a salt or water shortfall is more efficient than the response to salt surplus. Cl is the most abundant anion outside of cells and derives from food. The current epidemiological investigation examined the relationship between blood electrolyte levels and hypertension in a salt-consuming community. Fluid and electrolyte balance is necessary for postoperative and critically ill patients' metabolic care, gastrointestinal function, and nutrition. Artificial nutrition should be prescribed with the same care as other nutritional and pharmaceutical needs. Materials and Methods: Secondary study of epidemiological study was carried out at the Government Medical College, Jagitial, India, which was carried out between the December 2021 to November 2022. Using regression models, the relationship between the amounts of sodium, potassium, chloride, total calcium, phosphate, and magnesium in the serum and blood pressure and the presence or absence of hypertension was investigated