Abstract: Background: Leukoplakia is the term used to recognize white plaques of questionable risk having excluded (other) known diseases or disorders that carry no increased risk for cancer. Leukoplakia is clearly a clinical term with no specific histology. The histological sections reveal atrophy or hyperplasia (acanthosis), hyperkeratosis and with or without epithelial dysplasia or carcinoma. WHO states that based on geographical location prevalence of oral leukoplakia ranges from 0.1% to 10.6% and India has a significantly higher number of cases. This article focused on extracting the scientific literature on leukoplakia from Central India published in Web of Science database. Methodology: Using specified Search Query with selected keywords, the Web of science database was accessed and publications arising from Central India were extracted. The file was imported and analysed using R-Studio Application. Results:Main list of publications included 188 documents from 125 sources. Majority were Journal articles. Most corresponding authors were from India whereas a few authors were from 9 other countries including US, France, Canada and Germany. Collaboration Index was 4.39. Annual Percentage Growth Rate of publications was 3.21. Conclusion: Scientific Productions on Leukoplakia from Central India as a special entity are on rise over a period of last 10 years. Researchers are more focussed on searching the rate of progression of leukoplakia and effectiveness of early diagnosis and treatment on the progress of leukoplakia to well-developed squamous cell carcinoma.