Cleft lip and palate is one of the most common congenital anomalies occurring round the world varyingwith the race, ethnicity and geography. Cleft lip and/or palate problems tends to worsen as the individualgrows older. Although it occurs as a different entity in itself but its presence can hamper aesthetics as wellas functions by effecting growth, dentition, speech, hearing and overall appearance resulting in socialand psychological problems for the child as well as the parents. Cleft lip and palate is of a multifactorialorigin such as inheritance, teratogenic drugs, and nutritional deficiencies and can also occur as syndrome or non-syndromic cleft. Treatment of Cleft Lip and Palate comprises of different specialists having anindividual insight in a particular case ultimately reaching to a consensus for a successful culminationof the treatment. Although appropriate timing and method of each intervention is still arguable. Anorthodontist plays a role in pre surgical maxillary orthopaedics, in aligning the maxillary segments anddentition, in preparation for secondary alveolar bone grafting and finally in obtaining ideal dental relationand preparing the dentition for prosthetic rehabilitation or orthognathic surgery if required. Therefore, forefficient treatment outcome and refinement of individual techniques or variations of the treatment protocol highly able team of specialists from different specialities is a must, preferably on a multicentre basis.