Background: TXA or Tranexamic acid has gained in significance in reducing blood loss in various gynaecological, oncological and orthopaedic surgeries. Its role in plastic surgical procedures is relatively new. TXA in reducing blood loss and ecchymosis in gynecomastia surgeries specifically has not been studied and no enough literature exists. Methods: Authors studied 20 consecutive cases operated by a single surgeon retrospectively, ten of whom had received TXA and other had not. The peri-operative blood loss by seeing the lipo-aspirate and ecchymosis were looked for on post-operative day. Results: The lipo-aspirate was clearer in TXA group and bloodier in non TXA group. None of the TXA group had ecchymosis while 3 had ecchymosis in non TXA group. Conclusion: TXA appears to reduce blood loss and chances of ecchymosis in gynecomastia surgeries. Level of evidence: 4.