The most common disease affecting the maxillary sinus is of odontogenic origin. Dental practitioners should be aware about the pathologies related to maxillary sinus and its relationship to maxillary dentition and supporting structures. After the introduction of Cone Beam Computed Tomography (CBCT), it has become the imaging modality of choice for clinicians in evaluating maxillary sinuses and maxillofacial structures. Three-dimensional (3D) imaging can be achieved by CBCT, which offers volumetric data about sinus pathologies and relationship between the maxillary teeth roots and the antrum with relatively low radiation doses and costs. CBCT is also capable of guiding the clinicians in final diagnosis, treatment planning and follow up. This review aims to emphasize the role of CBCT in the detection of maxillary sinus pathologies in day to day dental practice. Further studies using 3-D visualization in sinus pathologies will yield a fundamental data & guidelines for future research. However, more research is required to authenticate its use in odontogenic maxillary sinusitis.