Background: The present study was conducted for evaluating anesthetic management in cesarean section of pregnant women with placental anomaly. Materials & Methods: Records of a total of 100 patients who underwent cesarean section were enrolled. Complete demographic and clinical details of all the subjects was obtained from record files. Only those patient’s data were enrolled among which confirmed diagnosis of placental location and invasion anomaly was present. All the patients were divided into two study groups as follows: Group A: Included patients with placenta previa (PP), and Group B: patients with placenta accreta (PA). The level of emergency of the operation, anesthetic method and interventional procedures was recorded separated in a Performa. Results: Data of 100 patients were divided into two study groups as follows: Group A: Included patients with placenta previa (PP), and Group B: patients with placenta accreta (PA); with 50 patients in each group. Significantly higher operative time and lower gestational age was seen among subjects of group B in comparison to group A. Most of the subjects of group B underwent C section under general anesthesia. Time for mechanical ventilation, duration of ICU stays and blood loss was significantly higher among subjects of group B.