Online ISSN: 2515-8260

RESEARCH ON POLYMORPHISM OF MATRIX METALLOPROTEINAS AND GROWTH FACTOR GENES IN PATIENTS WITH PHOTO AGING AND WITH MELASMA

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Nigora Khodjaeva,Ulugbek Sabirov,Shahnoza Mavlyanova,Sevara Muminova,

Abstract

Abstract: In patients with a genetic predisposition, associations of the mutant variants Arg25Pro of the TGFb1 gene, A-8202G of the MMP9 gene and MMP1 1607G (9.6%), associations of the mutations of the Arg25Pro gene of the TGFb1 gene, and A-8202G of the MMP9 gene (5.8%) are mainly detected, associations of mutations of Arg25Pro genes of TGFb1 and MMP1 1607G (3.8%), associations of mutations of A-8202G genes of MMP9 and MMP1 1607G (15.4%) of the examined patients with photo-aging.

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