Background and Aim: In dentistry tooth extraction is routine minor oral surgical procedure. But patients have fear of painful injection for local anaesthesia. For maxillary tooth need to apply buccal and palatal prick for local anaesthesia. Out of this palatal injection is very painful. The aim of this prospective, randomized study is to demonstrate whether 4% articaine hydrochloride administered alone as a single buccal infiltration in maxillary premolar tooth removal, can provide favourable palatal anesthesia as compared to buccal and palatal injection of 2% lidocaine.