ABSTRACT Background: Dental practice has risks to occupational health for the body in terms of ergonomics. Broadly speaking, ergonomics is the study of humans to create work systems that are healthier, safer, and more comfortable. Musculoskeletal disorders (MSDs) are disorders of the muscles, tendons, joints, vertebrae, peripheral nerves, and vascular system that can be caused by various factors, including occupational factors such as posture distortion, too long a static posture, and repetitive movements. Pupose: The purpose of this study was to determine the relationship between the level of awareness about ergonomics to Musculoskeletal Disorders (MSDs) in the dental profession students of Universitas Airlangga. Methods: Data were collected through online questionnaires and analyzed using the Pearson Chi-Square technique. Results: Out of 55 students, 100% (55) dentistry profession students were aware of the importance of ergonomics. Then 84.9% (45) students experienced symptoms of musculoskeletal abnormalities and another 15.1% (8) students did not experience musculoskeletal symptoms. Statistically, there is no significant relationship between the level of awareness about ergonomics towards Musculoskeletal Disorders (MSDs) in the dental profession students of Universitas Airlangga. Conclusion: The level of awareness about ergonomics is not significantly related to Musculoskeletal Disorders (MSDs) in the dental profession students of Universitas Airlangga.