The present prospective study on “incidence of contrast-induced nephropathy” was conducted on the patients admitted in the cardiac care unit. Total of 200 patients were taken. All the subjects included in the study underwent coronary / renal angiography using 50-60 ml of iohexol non-ionic radiopaque contrast media.All the patients were subjected to a detailed history, clinical examination and laboratory investigations which were recorded in the predesigned performa for this study.Following observations were made, More male patients (110; 55%) were observed than female patients (90; 45%) during the study period.Male to female ratio was 1.2:1.Most male patients 36 (32.7%) were observed in 50-59 years age group, followed by 28 (25.5%) in 60-69 years age group,followed by 17 (15.5%) in > 70 years age group.Similarly, female patients were 29 (32.22%) in 50-55 yr age group, followed by 20 (22.22%) in60-69 years age group followed by 16 (17.77%) in > 70 years age group. Conclusion: Contrast media (CM) are increasingly used in diagnostic and interventional procedure. This results in the rising incidence of iatrogenic renal function impairment caused by exposure to CM, a condition known as CIN