ABSTRACT Background: Autopsy (necropsy, post mortem examination, thanatopsy) is the meticulous and thorough examination of a person’s body after death. An autopsy can be of different types. To the forensic pathologist, Medicolegal autopsy is the most important concern. Study of weight of human body organs plays a significant role in almost all the branches of medical sciences as any deviation in weight from the normal range may suggest some pathological change in the organ. Recording of organ weights is one of regular criteria by the forensic experts during an autopsy. The findings were compared to what is standard or average of a specific organ for a specific age range and particular sex. The determination of weights of brain in particular has significant clinical value. Materials and Methods: After getting institutional ethical committee clearance, the study conducted over the body of the 570 deceased came for medicolegal autopsy fulfilling the inclusion and exclusion criteria. Results: Total 570 cases had been selected after following the inclusion and exclusion criteria out of which 362 were males and 208 were females. Among the studied 570 cases, 362 (63.5 %) were male and rest (36.5 %) were female. In this study the discussion was mainly on relation of age, sex, body weight, and body length upon the weight of brain. Conclusion: A database may be deduced from this study regarding normal range of the weight of various organs and their relation with external parameters of the subjects which can be applicable on the population of this region for future reference. In severely mutilated bodies found in mass disasters or in homicidal killing, weights of isolated organs may give an idea about the stature, built and age of the victims helping in identification.