The shocking worldwide transmission of COVID-19 has encouraged many governments to interfere to avoid the spread of the infection. Medical tourism is a growing phenomenon with policy implications for health systems, particularly of destination countries. Medical tourism, a rapidly growing market, has been recognized by many countries as a potential sector for economic diversification. Although Singapore stands out as one of the top destinations of medical tourism, investigation regarding its competitiveness has been limited and narrow in scope. This case study takes a quantitative approach to identify and analyze the factors that position Singapore as a competitive medical tourism destination. Based on a holistic approach, this study has shown that integrating diverse strategies for medical tourismdevelopment with sound government policies and proactive management practices have led to significant positive outcomes towards mutual success of tourism and healthcare sectors of Singapore. Additionally, the study provides strategic insights to drive lasting improvements in medical tourism, exchange rare and service sectors through efficient management and intelligent utilization of resources in tourism sector.