ABSTRACT: Platelets plays an important role in hemostasis by preventing blood loss at the site of vascular injury. The growth factors in platelets has been believed to have the potential to accelerate the healing process, promotes tissue repair and regeneration. The platelet rich growth factor promotes both hard (bone) and soft (skin and gingival) tissue healing. The PRP has a broad spectrum of applications in oral and maxillofacial surgery. This review article presents with various applications of PRP in maxillofacial surgery.