Dengue fever" (DF) is a serious public health issue, particularly in South Eastern parts of Asia. Biochemical changes have been proven to be early indicators of DF. This study was done on 90 DF patient to investigate the influence of the disease on liver functions along with lipid profiles and to link the results with the degree of seriousness of the disease.The current cross-sectional and observational study included 90 participants. Frequency and percentage were used to express qualitative data. The experimental investigation comprised a DF test with a quick diagnostic kit, liver function testing, and lipid profile tests. Quantitative data was reported utilizing the "mean standard deviation" as well as "median". The majority of the patients (55.6 percent) were males, with the remainder (44.4 percent) females, for a male to female ratio of 1.25 to 1. Raised "aspartate aminotransferase" (AST) was detected in 84.4% of patients, total bilirubin was found in 15.6%, and serum albumin was found in 56.7%. However, no significant relationship was discovered between ages and the intensity of Dengue. Meanwhile, there was a significant correlation (p0.05) between the result of liver performance tests as well as the severity of Dengue, with impaired liver function rising with increasing severity.