Background&Method: Laparoscopic drainage of liver abscesses in combination with systemic antibiotics is a safe and useful alternative in all patients who require surgical drainage following failed medical or percutaneous drainage treatment and in those with large abscesses. Operative techniques have started on intravenous antibiotics and the laparoscopic procedure was performed under general anaesthesia with endotracheal intubation. The patient was placed in the reverse Trendelenburg position and a pneumoperitoneum was created with a veres needle to a pressure of 09-12 mm Hg. Result: Pain in the right upper abdomen, fever and hepatomegaly were the most common presenting features in 99.5% of patient. History of alcoholic intake leading to liver abscess was 36%, while 36.84% of cases presented with mid jaundice. History of past dysentery was 34.21%. In the study by Abuabara etal(1982), the most common symptom of ALA was Right upper abdominal pain (94%), fever (77%) and hepatomegaly(54%). In the study by Charles etal(1989), the most common symptom was fever(70-80%), hepatomegaly (56-65%), right upper abdominal pain (50%). Hematological investigation were carried out in all patients the mean hemoglobin value was 10.1 gm/dL with a range of 5.0 gm% to 14.5 gm%. Leucocytosis, predominantly polymorphonuclear was observed, the mean leucocyte count was 13,500 cells/cumm with a range of 5,500-32,000 cells/cumm. The serum bilirubin was elevated in 60 (101) cases, the values ranging from 1.8-17 mg% with a mean of 3.39 mg%. Hypoproteinemia was observed in majority of cases,the values ranging from 4.8-8.9 mg/dl with a mean value of 6.47mg/dl. Conclusion: In summary , the most common presenting features were Fever, Hepatomegaly, with males in the age group 41-50 being mostly affected. Right lobe involvement (singly) with raised dome of diaphragm were seen most commonly on radiological investigations. PLA should be treated with broad spectrum antibiotics and in abscesses larger than 2.5 cm, aspiration should be done. Operative intervention is required for intra-abdominal infections that are seeding the liver abscess.