Background: Establishing whether patients are exposed to a ‘known cause’ is a key element in both the diagnostic assessment and the subsequent management of hypersensitivity pneumonitis (HP). Objective: The aim of the study is to determine the burden of hypersensitivity pneumonitis at a respiratory center. Methods: 100 patients had been enrolled to the study. Demographic, clinical, radiological and aetiological data were collected with a random identification code for each patient in view of maintaining the confidentiality during data collection. Results: Out of 100 patients, there were 65 females and 35 males. Mean age of the population was 55.50 years (SD = 10.50) years. 50 patients were less than 65 years of which 30 were aged between 45 to 60 years while 20 were aged <5 years. Conclusion: In general, patients with acute disease, if correctly and timely diagnosed and treated, have a good prognosis, and patients usually improve. By contrast, patients with subacute/chronic HP (in particular those with bird fancier’s disease) often progress to irreversible pulmonary fibrosis and may die within a few years after diagnosis.