The field of probiotics is an evolving field. Time has come to shift the paradigm of treatment from specific bacteria elimination to altering bacterial ecology by probiotics. Probiotics are dietary supplements containing potentially beneficial bacteria or yeasts. Probiotics have been found to be beneficial to the host health by improving the endogenous flora. Traditionally, probiotics have been associated with gastrointestinal tract, however recently several investigators have suggested use of probiotics for oral health.