Cutaneous leishmaniasis, is a diseases transmitted by sand-flies, which infect both genders and all age groups; the study was conducted in Al-Najaf /Iraq, during the period (September 2018 - April 2019). Data collected from four Hospitals (Al-Sadr Teaching Hospital, Al-Hakeem Teaching Hospital, Al-Forat Teaching Hospital and AlSajad Teaching Hospital). Data included 321 patients of both genders aged (≤10- ≥51),from urban and rural areas and different occupations; infection was Clinically examined by a physician (skin specialist).The results recorded high rate of infection with cutaneous leishmaniasis during the period of the study, in January reaching to 26.7 % ,While it was less in April 7.7 %, with a statistical significance between months of the study, also results indicated that the highest infection was in age range (11-21 ) year old reach to 7.7 according to age groups. Also the results showed the high rate of infection in males reaching to 9.3 as compared in females, with statistical significance between age groups and gender. The results showed that the highest incidence was 33% on the patients’ hands, multiple lesions more than single lesion, with significant differences between number and location of lesions on the patient's body. In the present study, the results state that leishmaniasis is prevalent in rural (54.3%) more than in urban areas (45.7 %.), also the military is more susceptible to infect with leishmaniasis .As compared with other occupations with significant differences between rural and urban areas as well as different occupations.